Sexual Function, Activity and Distress 24 Months After Surgical Menopause: What Happens After Menopause (WHAM)—A Prospective Controlled Study

Abstract

Objective: To determine the effect of surgical menopause (risk-reducing salpingo-oophorectomy, RRSO) on sexual function and the modifying effects of HRT. Design: Prospective observational study of women undergoing RRSO and age-matched comparison group who retained their ovaries. Setting: High-risk clinics and general population. Methods: Sexual function was measured at baseline, 3, 6, 12 and 24 months. Main Outcome Measures: Primary outcome was sexual function at 24 months using the Female Sexual Function Index (FSFI). Secondary outcomes included the Fallowfield Sexual Activity Questionnaire (SAQ) and Female Sexual Distress Scale-Revised (FSDS-R). Results: Baseline sexual function was simila..